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April

Research Fellow

Monash University - Monash, ACT

Education, Childcare & Training
Source: uWorkin

JOB DESCRIPTION

  • Be inspired, every day
  • Drive your own learning at one of the world's top 80 universities
  • Take your career in exciting, rewarding directions
Everyone needs a platform to launch a satisfying career. At Monash, we give you the space and support to take your career in all kinds of exciting new directions. You'll have access to quality research, infrastructure and learning facilities, opportunities to collaborate internationally, as well as the grants you'll need to publish your work. We're a university full of energetic and enthusiastic minds, driven to challenge what's expected, expand what we know, and learn from other inspiring, empowering thinkers.

An exciting opportunity exists for a Research Fellow to join the department of Infectious diseases within Central Clinical School. The appointee will use computational biology approaches to investigate capsule locus diversity and genomic epidemiology of Klebsiella pneumoniae, a World Health Organization priority pathogen. K. pneumoniae has been listed as a priority target for development of novel control strategies due to growing rates of multi-drug resistant strains that are extremely difficult to treat. Its polysaccharide capsule is a key vaccine target, and genomic analysis of its capsule synthesis loci has indicated extensive capsule type diversity across the population. However, until now there has been limited serological typing data with which to fully understand the relationship between capsule genotype and phenotype, which is a key prerequisite for successful vaccine design. In collaboration with researchers at the Statens Serum Institut (Denmark), we aim to address this knowledge gap through fine-scale analysis of K. pneumoniae capsule synthesis loci and comparison to newly generated serological typing data. The appointee will contribute to this and related projects by performing the comparative genomic analyses, interpreting the data and contributing to results communication.

To be appointable into this role you will have a doctoral degree or equivalent level of research experience with a strong bacterial genetics and/or computational microbiology component, and experience working with DNA sequence data and annotations. Experience using basic command-line tools for data analysis and/or the R programming language is also desirable.

This role is a full-time position; however, flexible working arrangements may be negotiated.

At Monash University, we are committed to being a Child Safe organisation. Some positions at the University will require the incumbent to hold a valid Working with Children Check.

Your application must address the selection criteria. For instructions on how to apply, please refer to " ".

Enquiries

Dr Kelly Wyres,

Monash University